The integration of CFD modeling and simulation is emerging as a game changer in the life sciences industry. For pharmaceutical companies, STAR-CCM+ is the ideal analysis invironment to develop continuous manufacturing of Active Pharmaceutical Ingredients (APIs) which leads to shorter product-process development cycles, reduced energy requirements, superior products and shorter time-to-market.
STAR-CCM+ also opens the door to explore innovative medical device designs and to aid the decision-making process for biomedical diagnostics by providing a means of gaining insight into delicate, often inaccessible areas.
STAR-CCM+ offers solutions for the Life Sciences Industry in areas including, but not limited to:
Mixing : The Eulerian multiphase model in STAR-CCM+ provides an effective means for modeling multiphase flows and is ideal for studying phases dispersed randomly in static mixers, stirred tanks, homogenizers and emulsifiers. The extensive range of sub-models provided by STAR-CCM+ include drag, virtual mass, lift and turbulent drag forces, break-up and coalescence models for bubbles, and a granular flow model.
Solids Handling : STAR-CCM+ includes a Discrete Element Modeling (DEM) capability that is fully coupled with a numerical flow simulation. DEM simulates the motion of a large number of interacting discrete particles and tracks the interaction between every particle in a numerically efficient manner, modeling contact forces and energy transfer due to collision and heat transfer between particles. STAR-CCM+ leads to solids handling solutions, whether one wants to analyze the chaotic movement of particles in fluidized beds, improve tablet coating uniformity, or filter particles in medical devices.
Fluid-Structure Interaction (FSI) : The complex FSI problems in the biomedical device industry are driven by highly compliant vessels and membranes that are structurally impacted by mechanical devices. STAR-CCM+ has a direct link to Abaqus finite element analysis through a co-simulation API developed by SIMULIA, delivering a fully coupled, implicit, two-way FSI and providing automation, efficiency and solution stability. This capability can handle FSI problems with ease, including respiratory/lung, coronary or carotid artery, heart valve and aneurism applications all the way to models of blood pumps such as LVADs coupled with patient-specific data.
Design: Optimate, a module in STAR-CCM+, enables intelligent design exploration and allows users to easily consider “what if” scenarios to maximize operating performance during the manufacturing process, realize small improvements of biomedical devices or develop corrective systems through medical diagnostics.
Shorten Time-to-Market: STAR-CCM+ opens the door to explore innovative ways to reduce cost and shorten time-to-market for the manufacturing process as it offers acost-effective way to address scale-up problems when taking the processes from laboratory to full-scale production.